Analytical Methodologies for the Determination of Oseltamivir
نویسندگان
چکیده
Oseltamivir phosphate is an antiviral drug used in the treatment and prophylaxis of both influenza virus A and influenza virus B. Oseltamivir phosphate is an ethyl ester pro-drug that is rapidly and extensively metabolized by esterases in the gastrointestinal tract and liver to its active form, oseltamivir carboxylate. There are some analytical methods in the literature for the analysis of both compounds in the biological fluids and pharmaceutical preparations. In this work, we have recompiled these methods with the aim of to present the different options for the oseltamivir determination.
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